Kambli, who played 17 Tests and 104 ODIs for India, made as many as nine comebacks into the ODI team, but played his last Test way back in 1995. (TOI Photo)
Kambli was taken ill while he was driving from Chembur to Bandra and suddenly stopped the vehicle.
A policewoman on duty, Sujata Patil noticed he could not drive and arranged to rush him to Lilavati Hospital.
Hospital sources say he is under observation and undergoing various tests to determine his health condition.
Kambli had undergone angioplasty on two of his blocked arteries in July 2012.
The flamboyant left-hander hit two double-centuries and two hundreds in his first eight Test innings after earning a debut in 1993, but another three-figure knock in Tests eluded him.
Kambli played the last of his 17 Tests in 1995 before he had turned 24, finishing with 1,084 runs at an average of 54.20.
He also scored 2,477 runs in 104 one-day internationals with two centuries. Kambli announced his retirement from international cricket in 2009 while he retired from first-class cricket in 2011.